According to a new analysis, four genes were uncovered that determine nose shape. The study’s evidence will aid scientists in understanding the origin of the variations in nose shapes, researchers claimed. “Finding out the role each gene plays helps us to piece together the evolutionary path from Neanderthal to modern humans,” study participant and co-author, Kaustubh Adhikari, a cell and developmental biologist at University College London, said in a statement. “It brings us closer to understanding how genes influence the way we look, which is important for forensics applications.”
Nose shape is ascribed to facial aesthetics, but analysts surmise that the different shapes evolved according to environmental divergence. The study’s lead author and biologist at the University College London, Andrés Ruiz-Linares, said, “For example, the comparatively narrower nose of Europeans has been proposed to represent an adaptation to a cold, dry climate,” and “Identifying genes affecting nose shape provides us with new tools to examine this question, as well as the evolution of the face in other species.”
The study incorporated 6,000 subjects from Colombia, Peru, Brazil, Chile and Mexico who had cooperated in the CANDELA study, an ongoing observation of the biological diversity of populations living in Latin America. This particular culture was chosen because of its ethnic diversity consisting of Caucasian, African and Native American ancestry causing a wide spectrum of facial features. Prior research conducted in this region led to the discovery of genes that cause people to go gray.
Scientists detailed participants’ facial characteristics and administered a 3D reconstruction for each of the 3,000 subjects. Then particular genomes were studied, which indicated three genes that drive bone and cartilage growth that also determined nose shape. Two of the genes, GLI3 and PAX1, largely affected nostril width, as another, DCH2, predicted nose pointiness. And a fourth gene, called RUNX2, was correlated with the breadth of the nose.
The three genes, however, only changed during humans’ modern evolutionary period in contrast to ancient history such as during the era of the Neanderthals and the Denisovans. Scientists conclude that these genes adapted to environmental pressures. The study’s details were published May 19th in the journal Nature Communications. The report was originally published in Discovery News.